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Dr. Savic joined the Department of Radiology at Charité Berlin, Germany as a research scientist and radiology resident upon completion of her postdoctoral fellowship in the Yale Interventional Oncology Lab, New Haven, USA. Dr. Savic’s research is dedicated to designing molecular imaging probes and developing new quantitative imaging biomarkers for liver cancer in the context of loco-regional therapies. Her deep interest in interventional oncology started with her doctoral research at the Johns Hopkins University and Charité, where she initially investigated molecular therapies that target altered tumor metabolism as a hallmark of cancer aggressiveness. After completing her thesis with summa cum laude, she served as a postdoctoral research fellow at Charité and at the Yale Interventional Oncology Lab, where she was supported by the Leopoldina postdoc fellowship.
During her postdoc, Dr. Savic was responsible for the preclinical portion of an NIH R01-funded study, which investigated multimodality imaging of the metabolic and immunologic components of the tumor microenvironment of liver cancer after transarterial chemoembolization (TACE). This research led to the development of non-invasive MRI biomarkers for the characterization of cancer hallmarks for which she was accredited as a co-principal investigator on a seed grant provided by the Society of Interventional Oncology.
Dr. Savic developed expertise in basic science methodologies and translational animal models for hepatobiliary cancer, including the VX2 rabbit tumor model. Her prior clinical research as part of two prospective trials was designed to establish Lipiodol as an imaging biomarker for precision medicine and prediction of tumor response as well as pharmacokinetics of doxorubicin after conventional TACE. Additionally, she helped establish advanced image analysis instruments for software-assisted evaluation of tumor response to loco-regional therapies.
Dr. Savic is the co-manager of the "Rising Star" Student Exchange Program in collaboration with the Yale Interventional Oncology Lab, which provides scientific mentoring for over 20 medical and doctoral students.