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Abdominal Imaging Research Group (AIM)

Die Abdominal Imaging Research Group (AIM) / AG Abdominale Bildgebung beschäftigt sich modalitätenübergreifend mit dem gesamtem Spektrum der Forschung zu abdominalen Organen und Erkrankungen.

     

Sie befinden sich hier:

Schwerpunkte und Projekte

Schwerpunkte:

  • Funktionelle und quantitative Leberbildgebung (Gd-EOB, Perfusion, IVIM, Oxygen-Enhanced MRI, MR-Spektroskopie, T1/T2/T1ρ-Mapping, AI, Radiomics)
  • Body Composition Imaging
  • Dual Energy-Bildgebung
     
  • Diffuse und biliäre Lebererkrankungen (NAFLD / NASH / PSC)
  • Neuroendokrine Tumoren
  • Hepatozelluläres Karzinom
  • Pankreaskarzinom
  • Transplantationen

Arbeitsgruppenleiter

Prof. Dr. med. Dominik Geisel

Geschäftsführender Oberarzt, Campus Virchow-Klinikum (CVK)

Stellvertretender Arbeitsgruppenleiter

Wissenschaftlicher Koordinator

Studenten und Doktoranden

  • Patricia Bady
  • Aboelyazid Elkilany
  • Pia Gabriel
  • Moritz Haase
  • David Petschelt
  • Martin Lupa
  • Anna Meyerhofer
  • Philipp Raabe
  • Miguel de Sousa Mendes
  • Ani Tsereteli
  • Krastina Videv
  • William Wienbrandt

Publikationen (Auswahl):

Elkilany A, Geisel D, Müller T, Fischer A, Denecke T. (2021)
Gadoxetic acid-enhanced MRI in primary sclerosing cholangitis: added value in assessing liver function
and monitoring disease progression

Abdom Radiol (NY) https://dx.doi.org/10.1007/s00261-020-02731-z

Steffen IG, Weissmann T, Rothe JH, Geisel D, Chopra SS, Kahn J, Hamm B, Denecke T. (2021)
Does Hepatic Steatosis Influence the Detection Rate of Metastases in the Hepatobiliary Phase of Gadoxetic Acid-Enhanced MRI?
J Clin Med. https://dx.doi.org/10.3390/jcm10010098

Haber PK, Maier C, Kästner A, Feldbrügge L, Ortiz Galindo SA, Geisel D, Fehrenbach U, Biebl M, Krenzien F, Benzing C, Schöning W, Pratschke J, Schmelzle M. (2021)
Predicting the Risk of Postoperative Complications in Patients Undergoing Minimally Invasive Resection of Primary Liver Tumors 
J Clin Med. https://dx.doi.org/10.3390/jcm10040685

Auer TA, Walter-Rittel T, Geisel D, Schöning W, Schmelzle M, Müller T, Sinn B, Denecke T, Hamm B, Fehrenbach U. (2021)
HBP-enhancing hepatocellular adenomas and how to discriminate them from FNH in Gd-EOB MRI
BMC Med Imaging. https://dx.doi.org/10.1186/s12880-021-00552-0

Fehrenbach U, Auer TA, Schöning W, Schmelzle M, Jürgensen C, Malinka T, Bahra M, Geisel D, Denecke T. (2021)
Postoperative single-sequence (PoSSe) MRI: imaging work-up for CT-guided or endoscopic drainage indication of collections after
hepatopancreaticobiliary surgery

Abdom Radiol (NY) https://dx.doi.org/10.1007/s00261-021-02955-7

Fehrenbach U, Thiel R, Bady PD, Auer TA, Kahl A, Geisel D, Lopez Hänninen E, Öllinger R, Pratschke J, Gebauer B, Denecke T. (2021)
CT fluoroscopy-guided pancreas transplant biopsies: a retrospective evaluation of predictors of complications
and success rates

Transpl Int. https://dx.doi.org/10.1111/tri.13849

Theilig, D., Mayerhofer, A., Petschelt, D., Elkilany, A., Hamm, B., Gebauer, B., Geisel, D. (2020).
Impact of interventionalist’s experience and gender on radiation dose and procedural time in CT-guided interventions—a retrospective analysis of 4380 cases over 10 years
European Radiology https://dx.doi.org/10.1007/s00330-020-07185-x

Hindel, S., Geisel, D., Alerić, I., Theilig, D., Denecke, T., Lüdemann, L. (2020).
Liver function quantification of patients with portal vein embolization using dynamic contrast-enhanced MRI for assessment of hepatocyte uptake and elimination
Physica Medica 76(), 207-220. https://dx.doi.org/10.1016/j.ejmp.2020.07.002

Theilig, D., Petschelt, D., Mayerhofer, A., Hamm, B., Gebauer, B., Geisel, D. (2020).
Impact of quantitative pulmonary emphysema score on the rate of pneumothorax and chest tube insertion in CT-guided lung biopsies
Scientific Reports 10(1), 10978. https://dx.doi.org/10.1038/s41598-020-67348-0

Fehrenbach, U., Gül-Klein, S., Mendes, M., Steffen, I., Stern, J., Geisel, D., Puhl, G., Denecke, T. (2020).
Portosystemic shunt surgery in the era of TIPS: imaging-based planning of the surgical approach
Abdominal Radiology 45(9), 2726-2735. https://dx.doi.org/10.1007/s00261-020-02599-z

Auer, T., Fehrenbach, U., Grieser, C., Penzkofer, T., Geisel, D., Schmelzle, M., Müller, T., Bläker, H., Seehofer, D., Denecke, T. (2020).
Hepatocellular adenomas: is there additional value in using Gd-EOB-enhanced MRI for subtype differentiation?
European Radiology 30(6), 3497-3506. https://dx.doi.org/10.1007/s00330-020-06726-8

Theilig, D., Münzfeld, H., Auer, T., Feldhaus, F., Krüger, A., Dürr, M., Geisel, D. (2020).
The Renal Resistive Index in Allografts: Is Sonographic Assessment Sufficiently Reproducible in a Routine Clinical Setting? – Reproducibility of the Renal Resistive Index 
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 192(06), 561-566. https://dx.doi.org/10.1055/a-1086-5191

Theilig, D., Elkilany, A., Jann, H., Roderburg, C., Hamm, B., Fehrenbach, U., Geisel, D. (2020).
Evaluating hepatotoxic effects of chemotherapeutic agents with gadoxetic-acid-enhanced magnetic resonance imaging
European Journal of Radiology 124(), 108807. https://dx.doi.org/10.1016/j.ejrad.2019.108807

Muenzfeld, H., Mahjoub, S., Roehle, R., Pelzer, U., Bahra, M., Boening, G., Hamm, B., Geisel, D., Auer, T. (2019).
Split-bolus vs. multiphasic contrast bolus protocol in patients with pancreatic cancer or cholangiocarcinoma
European Journal of Radiology 119(), 108626. https://dx.doi.org/10.1016/j.ejrad.2019.07.027

Theilig, D., Tsereteli, A., Elkilany, A., Raabe, P., Lüdemann, L., Malinowski, M., Stockmann, M., Pratschke, J., Hamm, B., Denecke, T., Geisel, D. (2019).
Gd-EOB-DTPA-enhanced MRI T1 relaxometry as an imaging-based liver function test compared with 13C-methacetin breath test 
Acta Radiologica 61(3), 291-301. https://dx.doi.org/10.1177/0284185119861314

Theilig, D., Elkilany, A., Schmelzle, M., Müller, T., Hamm, B., Denecke, T., Geisel, D. (2019).
Consistency of hepatocellular gadoxetic acid uptake in serial MRI examinations for evaluation of liver function
Abdominal Radiology 44(8), 2759-2768. https://dx.doi.org/10.1007/s00261-019-02036-w

Fehrenbach, U., Kahn, J., Fahlenkamp, U., Baur, A., Pavel, M., Geisel, D., Denecke, T. (2018).
Optimized imaging of the lower abdomen and pelvic region in hepatocyte-specific MRI: evaluation of a whole-abdomen first-pass shuttle protocol in patients with neuroendocrine neoplasms 
Acta Radiologica 60(9), 1074-1083. https://dx.doi.org/10.1177/0284185118817936

Theilig, D., Steffen, I., Malinowski, M., Stockmann, M., Seehofer, D., Pratschke, J., Hamm, B., Denecke, T., Geisel, D.(2019).
Predicting liver failure after extended right hepatectomy following right portal vein embolization with gadoxetic acid-enhanced MRI 
European Radiology 29(11), 5861-5872. https://dx.doi.org/10.1007/s00330-019-06101-2

Stief, J., Haase, M., Lüdemann, L., Theilig, D., Schmelzle, M., Hamm, B., Denecke, T., Geisel, D. (2019).
Combined morphological and functional liver MRI using spin-lattice relaxation in the rotating frame (T1ρ) in conjunction with Gadoxetic Acid-enhanced MRI
Scientific Reports 9(1), 2083. https://dx.doi.org/10.1038/s41598-018-37689-y

Frisch, A., Walter, T., Grieser, C., Geisel, D., Hamm, B., Denecke, T. (2018).
Performance survey on a new standardized formula for oral signal suppression in MRCP 
European Journal of Radiology Open 5(), 1-5. https://dx.doi.org/10.1016/j.ejro.2017.12.002

Malinowski, M., Geisel, D., Stary, V., Denecke, T., Seehofer, D., Jara, M., Baron, A., Pratschke, J., Gebauer, B., Stockmann, M. (2015). 
Portal vein embolization with plug/coils improves hepatectomy outcome 
Journal of Surgical Research 194(1), 202-211. https://dx.doi.org/10.1016/j.jss.2014.10.028

Geisel, D., Malinowski, M., Powerski, M., Wüstefeld, J., Heller, V., Denecke, T., Stockmann, M., Gebauer, B. (2014).
Improved Hypertrophy of Future Remnant Liver after Portal Vein Embolization with Plugs, Coils and Particles
CardioVascular and Interventional Radiology 37(5), 1251-1258. https://dx.doi.org/10.1007/s00270-013-0810-0

Geisel, D., Lüdemann, L., Hamm, B., Denecke, T. (2015). 
Imaging-Based Liver Function Tests – Past, Present and Future 
RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 187(10), 863-871. https://dx.doi.org/10.1055/s-0035-1553306

Geisel, D., Lüdemann, L., Gebauer, B., Fröling, V., Prasad, V., Heimann, U., Stockmann, M., Malinowski, M., Hamm, B., Brenner, W., Denecke, T. (2014). 
Optimized separation of left and right liver lobe in dynamic 99mTc-mebrofenin hepatobiliary scintigraphy using a hybrid SPECT-CT scanner 
Annals of Nuclear Medicine 28(9), 897-902. https://dx.doi.org/10.1007/s12149-014-0883-0

Geisel, D., Raabe, P., Lüdemann, L., Malinowski, M., Stockmann, M., Seehofer, D., Pratschke, J., Hamm, B., Denecke, T. (2017). 
Gd-EOB-DTPA-enhanced MRI for monitoring future liver remnant function after portal vein embolization and extended hemihepatectomy: A prospective trial 
European Radiology 27(7), 3080-3087. https://dx.doi.org/10.1007/s00330-016-4674-y

Geisel, D., Lüdemann, L., Keuchel, T., Malinowski, M., Seehofer, D., Stockmann, M., Hamm, B., Gebauer, B., Denecke, T. (2013). 
Increase in left liver lobe function after preoperative right portal vein embolisation assessed with gadolinium-EOB-DTPA MRI 
European Radiology 23(9), 2555-2560. https://dx.doi.org/10.1007/s00330-013-2859-1